What are the different
types of diabetes?
There are two major types
of diabetes, called type 1 and type 2.
Type 1 diabetes was also
called insulin dependent diabetes mellitus (IDDM), or
juvenile onset diabetes mellitus. In type 1 diabetes,
the pancreas undergoes an autoimmune attack by the body
itself, and is rendered incapable of making insulin.
Abnormal antibodies have been found in the majority
of patients with type 1 diabetes. Antibodies are proteins
in the blood that are part of the body's immune system.
The patient with type 1 diabetes must rely on insulin
medication for survival. In autoimmune diseases, such
as type 1 diabetes, the immune system mistakenly manufactures
antibodies and inflammatory cells that are directed
against and cause damage to patients' own body tissues.
In persons with type 1 diabetes, the beta cells of the
pancreas, which are responsible for insulin production,
are attacked by the misdirected immune system. It is
believed that the tendency to develop abnormal antibodies
in type 1 diabetes is, in part, genetically inherited,
though the details are not fully understood. Exposure
to certain viral infections (mumps and Coxsackie viruses)
or other environmental toxins may serve to trigger abnormal
antibody responses that cause damage to the pancreas
cells where insulin is made. These antibodies can be
measured in the majority of patients, and may help determine
which individuals are at risk for developing type 1
diabetes.
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